Klebsiella Pneumoniae Isolates and Genomic Data from Neonatal Sepsis Cases

1,523 Klebsiella pneumoniae isolates from neonatal sepsis cases across 27 units in 13 African and South Asian countries between 2013 and 2023. The dataset includes whole-genome sequence data used to estimate nosocomial transmission clusters and antimicrobial resistance gene profiles. It was created by Erkison Ewomazino Odih and shared under a CC-BY-4.0 license.

Use Cases

• Estimating nosocomial transmission burden based on pairwise temporal and genetic distances.
• Analyzing associations between antimicrobial resistance genes (e.g., ESBL, carbapenemase) and transmission clusters.
• Tracking the prevalence and spread of specific multi-locus sequence types (STs) across neonatal units.
• Investigating the role of globally recognized multidrug-resistant lineages in neonatal sepsis.

Strengths

• 1,523 bacterial isolates provide a substantial sample size for analysis.
• Data spans a 10-year period (2013-2023) across 13 countries, offering broad temporal and geographic coverage.
• Includes detailed genetic data enabling transmission cluster analysis and resistance gene profiling.

Limitations

• Row count for the tabular data is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The description notes a lack of sufficient clinical and facility-level data for high-resolution transmission dynamics.

Provenance

Source

Aggregated from 10 contributing studies.

Collection Method

Bacterial whole-genome sequencing of isolates from neonatal sepsis cases.

Time Range

2013 to 2023

Freshness

Last updated 2026-05-13 18:00:09; freshness should be verified.

Geography

27 neonatal units in 13 countries across Africa and South Asia.