Differentially Expressed Proteins from EV-Exposed HepG2 Cells

Celeste K. Carberry's dataset lists proteins with significantly differential expression following extracellular vesicle exposure conditions. It includes corresponding Log2 fold changes, p-values, and adjusted p-values. The dataset was last updated on March 18, 2026.

Use Cases

• Identify potential biomarkers for PFAS-induced liver toxicity based on differential protein expression.
• Perform pathway enrichment analysis using the list of significantly altered proteins.
• Validate miRNA target predictions by correlating with protein expression changes mentioned in the description.
• Investigate the role of extracellular vesicles in oxidative stress responses using the provided protein lists.

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• Specific statistical metrics (Log2 fold change, p-values, adjusted p-values) are provided for each protein.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Celeste K. Carberry.

Collection Method

Likely derived from proteomic analysis of treated HepG2 cells.

Freshness

Last updated 2026-03-18 17:35:38; freshness should be verified.