LC-MS data identifies host proteins interacting with the pathogenic fungus Lomentospora prolificans. The 19.3 KB XLSX file, published by Povilas Kavaliauskas on figshare in April 2026, lists protein hits from pulldown experiments on airway epithelial cells. It provides evidence that integrin β4 serves as a receptor for fungal adhesion.
Use Cases
- Identify potential host receptors for fungal pathogens based on LC-MS protein hit lists.
- Compare protein interaction profiles between Lomentospora prolificans and related species Scedosporium apiospermum and boydii.
- Validate fungal adhesion mechanisms through analysis of host proteins like integrin β4.
- Investigate non-proteinaceous fungal ligands using data from proteinase K and heat-killed conidia treatments.
Strengths
- Data is directly linked to a published study on a novel fungal adhesion mechanism.
- File is small (19.3 KB) and in a standard XLSX format for easy access.
- Released under a permissive CC-BY-4.0 license for reuse.
Limitations
- Row count and column-level documentation are unknown, limiting suitability assessment.
- The dataset scope is limited to protein hits from a specific experimental setup.
- Data may reflect the specific experimental bias of the pulldown and LC-MS methodology.
Provenance
- Source
- figshare, author Povilas Kavaliauskas.
- Collection Method
- Generated from whole fungal cell pulldowns of surface proteins from airway epithelial cells followed by liquid chromatography-mass spectrometry (LC-MS).
- Time Range
- null
- Freshness
- Last updated 2026-04-08 17:43:39.
- Geography
- null