Literature-Supported Protein Roles in Liver Health Pathways

A literature-curated dataset linking differentially expressed proteins and enriched pathways to liver health outcomes. The dataset was created by Celeste K. Carberry and last updated in March 2026. It is a small dataset, 9.5 KB in size, stored in an XLS file.

Use Cases

• Validate predicted protein-pathway relationships in the context of liver disease based on the described literature support.
• Investigate the functional role of extracellular vesicles in PFAS-mediated liver toxicity as suggested by the description.
• Study the link between oxidative stress pathways and liver disease progression using the implicated protein references.
• Support systems biology analyses of PFAS mixture toxicity in HepG2 cell models as indicated by the platform tags.

Strengths

• Dataset is licensed under CC-BY-4.0, allowing for open sharing and adaptation.
• Each protein-pathway link is supported by associated literature references as described.

Limitations

• Row count and specific column definitions are unknown, limiting suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Celeste K. Carberry via figshare

Collection Method

Likely compiled from literature review and proteomic pathway analysis of treated HepG2 cells.

Freshness

Last updated 2026-03-18 17:35:48; freshness should be verified.