MAGMA Gene Mapping for Age-Related Eye Disease

11 genome-wide significant loci were identified for Age-related eye disease (ARED) using Genomic Structural Equation Modeling. This dataset, created by Luqi Gao and last updated in May 2026, presents prioritized candidate SNPs and gene signals from transcriptome-wide association analyses. The data is shared under a CC-BY-4.0 license as a 9.6 KB Excel file.

Use Cases

• Prioritizing candidate genes for ARED based on statistically prioritized SNPs
• Analyzing tissue- and cell layer-associated gene signals reflecting ocular vulnerabilities
• Conducting functional annotation of genetic variants in relation to ARED
• Validating findings from GWAS on a phenotype not directly measured

Strengths

• Identifies 11 genome-wide significant loci for ARED
• Applies multiple transcriptome-wide association approaches for analysis
• Provides functional annotations for identified gene signals

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

Luqi Gao via figshare

Collection Method

Genomic Structural Equation Modeling and Post-processing analysis of Genome-Wide Association Studies

Freshness

Last updated 2026-05-14 17:48:55; freshness should be verified