PLXNB1 Gene Expression in Allergic Rhinitis Olfactory Dysfunction

5.5 KB of differential gene expression analysis results from GEO datasets GSE75011 and GSE43523. The dataset, authored by Xinglong Chen and last updated in 2026, focuses on identifying key genes linked to olfactory dysfunction in allergic rhinitis. It includes findings on PLXNB1 expression and its correlation with immune cell infiltration.

Use Cases

• Identify hub genes for olfactory dysfunction based on differential expression analysis mentioned in the description
• Validate gene targets for therapeutic intervention based on the identified PLXNB1 gene
• Analyze protein-protein interaction networks based on the constructed PPI network
• Investigate immune infiltration patterns in allergic rhinitis based on the correlation analysis described

Strengths

• Dataset is small (5.5 KB), facilitating quick download and initial inspection.
• Analysis is validated across two independent GEO datasets (GSE75011 and GSE43523).
• Findings are supported by in vitro and in vivo functional assays as described in the methods.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's 5.5 KB size indicates a very limited scope, likely containing summary results rather than raw data.

Provenance

Source

figshare

Collection Method

Differential gene expression analysis conducted on public GEO datasets.

Freshness

Last updated 2026-06-01 17:31:14; freshness should be verified.