Sex-Specific Correlates of IL-17A in a Zambian Adult Cohort

David Chisompola's dataset presents results from a cross-sectional study of 225 adults (71 males, 154 females) from Livingstone University Teaching Hospital in Zambia, last updated in May 2026. It contains the results of sex-stratified multiple linear regression models analyzing sociodemographic, clinical, and inflammatory correlates of circulating Interleukin-17A (IL-17A). The study identified distinct sex-specific determinants, with IL-6 and IL-1β positively correlating with IL-17A in males, while plasma potassium was the sole significant determinant in females.

Use Cases

• Training models to predict IL-17A levels based on inflammatory cytokine profiles in males.
• Analyzing sex-specific biomarker relationships for HIV-associated and cardiometabolic conditions.
• Investigating the role of plasma potassium as a determinant of IL-17A in female cohorts.

Strengths

• Dataset is based on a cohort of 225 participants with sex-stratified analysis (71 males, 154 females).
• Analysis includes a panel of inflammatory cytokines (e.g., IL-6, IL-1β, IFN-γ) and clinical variables like HIV status.
• Results are derived from multiple linear regression models with statistical significance (p < 0.05).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (5.5 KB), indicating limited scope, likely containing only model results.

Provenance

Source

David Chisompola via figshare.

Collection Method

Cross-sectional study using blood plasma measurements and clinical data collection.

Freshness

Last updated 2026-05-18 17:40:40; freshness should be verified.

Geography

Livingstone University Teaching Hospital, Zambia.