Mediation Analyses of Positive/Negative Affect in Bipolar Disorder Patients

Dongyu Han's dataset contains cross-sectional clinical assessment data from 124 Han Chinese patients with bipolar disorder, divided into groups based on early-stage antidepressant treatment history. The data includes scores from the Positive and Negative Affect Scale and the Barratt Impulsiveness Scale, used to analyze relationships between treatment, affect, and impulsivity. The dataset was last updated on 2026-04-22 and is shared under a CC-BY-4.0 license.

Use Cases

• Compare impulsivity and affect scores between patient groups based on antidepressant treatment history.
• Investigate correlations between negative affect and motor impulsivity as described in the study results.
• Perform mediation analysis to explore the role of affect in the relationship between antidepressant use and impulsivity.
• Replicate the study's statistical tests (t-tests, Mann-Whitney U, bootstrapping) on the provided clinical data.

Strengths

• Includes data from 124 clinically assessed patients, providing a defined sample size.
• Contains validated clinical scale scores (Positive and Negative Affect Scale, Barratt Impulsiveness Scale).
• Study design and statistical methods are explicitly described in the accompanying documentation.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 5.5 KB, indicating limited scope.

Provenance

Source

Dongyu Han via figshare

Collection Method

Cross-sectional study involving clinical assessments of 124 Han Chinese patients with bipolar disorder.

Freshness

Last updated 2026-04-22 17:33:48; freshness should be verified.

Geography

Likely China, based on the patient population being Han Chinese.