MendelVar: Prioritized Genetic Loci for Age-Related Eye Disease

Luqi Gao's research provides genetic association data for Age-Related Eye Disease (ARED). The dataset includes results from Genomic Structural Equation Modeling and post-processing of Genome-Wide Association Studies, identifying 11 genome-wide significant loci. It was last updated on May 14, 2026.

Use Cases

• Prioritize candidate SNPs for functional validation based on GWAS post-processing results.
• Analyze tissue- and cell layer-specific gene signals associated with age-related ocular vulnerabilities.
• Conduct functional annotation of genetic variants in relation to Age-Related Eye Disease (ARED).

Strengths

• Dataset is licensed under CC-BY-4.0, allowing for broad reuse.
• Analysis identified 11 genome-wide significant loci, providing concrete genetic targets.

Limitations

• The dataset is very small (17.4 KB), indicating limited scope.
• Row count and column-level documentation are unknown, complicating suitability assessment.
• Data freshness should be verified as the last update date is in the future (2026).

Provenance

Source

Luqi Gao

Collection Method

Generated using Genomic Structural Equation Modeling and post-processing analysis of Genome-Wide Association Studies.

Freshness

Last updated 2026-05-14 17:48:57