MendelVar Enrichment: Prioritized SNPs for Age-Related Eye Disease

11 genome-wide significant loci were identified for Age-related eye disease (ARED) using Genomic Structural Equation Modeling and post-processing of GWAS. The dataset likely contains prioritized candidate single nucleotide polymorphisms (SNPs) and functional annotations from transcriptome-wide association approaches. It was authored by Luqi Gao and last updated in May 2026.

Use Cases

• Prioritizing candidate genes for Age-related eye disease (ARED) based on statistically significant SNPs.
• Analyzing tissue- and cell layer-specific gene signals reflecting ocular vulnerabilities.
• Conducting functional annotation of genetic variants associated with independent ARED variants.

Strengths

• Identifies 11 genome-wide significant loci for Age-related eye disease (ARED).
• Applies multiple analytical methods, including Genomic-SEM and transcriptome-wide association approaches.
• Released under a permissive CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (17.4 KB), suggesting limited scope.

Provenance

Source

Luqi Gao

Collection Method

Genomic Structural Equation Modeling (Genomic-SEM) and post-processing analysis of Genome-Wide Association Studies (GWAS).

Freshness

Last updated 2026-05-14 17:48:57; freshness should be verified.