Mouse Blast Injury Visual Function Data

A neuroscience dataset contains experimental measurements from a mouse model of blast-induced traumatic brain injury. The data includes neurological severity scores, flash visual evoked potentials (F-VEP), and light-dark shuttle box results collected at multiple time points post-injury. The dataset supports research on biphasic visual dysfunction mechanisms.

Use Cases

• Analyze temporal patterns of visual dysfunction by comparing flash visual evoked potentials (F-VEP) results across multiple post-injury time points.
• Correlate neurological severity scores with ultrastructural damage evidence from transmission electron microscopy (TEM) to study injury progression.
• Investigate therapeutic effects by comparing neuronal pyroptosis marker levels before and after MCC950 treatment in bTBI mice.

Strengths

• Data includes multiple assessment modalities: neurological scores, electrophysiological F-VEP, behavioral light-dark box tests, and molecular markers.
• Experimental design includes a therapeutic intervention (MCC950) group for comparative analysis.
• Published under a permissive CC BY 4.0 license for reuse.

Limitations

• The dataset is very small at 73.4 KB, indicating limited sample size and scope for statistical modeling.
• Data is specific to a controlled mouse model, limiting direct applicability to human clinical studies.
• Column structure and sample data are unavailable, complicating immediate analysis.

Provenance

Source

figshare, authored by Yue Wang.

Collection Method

Data generated from a laboratory study using a biological shock tube to establish a blast-induced traumatic brain injury mouse model.

Time Range

Experimental time points include 24 hours and 28 days post blast exposure.

Freshness

Last updated March 2026.

Geography

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