Mouse Lung Single-Cell RNA Sequencing Samples for Tuberculosis Studies

Mouse lung single-cell RNA sequencing (scRNA-seq) samples collected by Fergal J. Duffy and last updated in April 2026. The dataset includes samples from four mouse lungs for each combination of timepoint, mouse strain, Mtb strain, and co-infection status. It is a small dataset of 5.5 KB, distributed under a CC-BY-4.0 license.

Use Cases

• Analyzing immune cell population changes based on different mouse strains and Mtb strains.
• Investigating transcriptional responses over different timepoints during infection.
• Studying the effects of co-infection (CoMtb) status on lung tissue gene expression.
• Comparing single-cell gene expression profiles across controlled experimental conditions.

Strengths

• Experimental design includes four biological replicates (n=4) per condition.
• Data is structured with controlled variables: timepoint, mouse strain, Mtb strain, and CoMtb status.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• The dataset is very small (5.5 KB), indicating limited scope.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Single-cell RNA sequencing of mouse lung tissue samples.

Time Range

Timepoints are listed but specific dates are not provided.

Freshness

Last updated 2026-04-27 17:26:30; freshness should be verified.

Geography

Laboratory mouse study; geographic origin is not specified.