A dataset containing NIH DAVID pathway analysis results from a study on Staphylococcus aureus metabolic adaptation. The data, authored by Reginald A. Woods and shared under a CC-BY-4.0 license, explores the link between the lipoic acid transfer enzyme LipL and the phosphotransacetylase (Pta) pathway in bacterial infection. It was last updated on May 4, 2026.
Use Cases
- Analyzing transcriptional coupling between pta and lipL genes based on the described functional link.
- Investigating metabolic flux through the Pta-AckA pathway based on the described acetate production defects in mutants.
- Studying the role of acetogenesis in skin and bloodstream infection outcomes based on the in vivo attenuation evidence.
- Examining protein-protein interactions, such as the direct interaction between Pta and LipL, based on the described mechanism.
Strengths
- Data is openly licensed under CC-BY-4.0, permitting reuse and redistribution.
- The 167.4 KB XLSX file suggests a focused, manageable dataset for analysis.
- The description provides a detailed biological context for the pathway analysis.
Limitations
- The dataset is very small (167.4 KB), indicating limited scope or a highly focused analysis.
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment for statistical modeling.
Provenance
- Source
- figshare
- Collection Method
- Likely generated from NIH DAVID bioinformatics tool analysis of experimental data.
- Time Range
- null
- Freshness
- Last updated 2026-05-04 17:48:06; freshness should be verified.
- Geography
- null