No. of F1s Screened: C. elegans Neuronal Microtubule Suppressor Screen Data

Sunanda Sharma's dataset, last updated April 15, 2026, contains results from a suppressor screen in C. elegans PLM mechanosensory neurons. The screen investigated factors like KLP-7, CITK-1/2, and ASPM-1 involved in microtubule stability and neuronal polarity. The data is stored in a 10.4 KB XLSX file.

Use Cases

• Validate suppressor screen hits for microtubule-associated genes based on the described neuronal ectopic extension phenotype.
• Analyze genetic interactions between citk-1/2 and aspm-1 based on the described shared pathway for microtubule plus-end dynamics.
• Correlate genetic variants with morphological defects in PLM neurons based on described neurite growth and synaptic branch defects.

Strengths

• Data is openly licensed under CC-BY-4.0.
• Dataset is small (10.4 KB), facilitating quick download and initial inspection.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The description is highly specific to a biological study, limiting generalizability.

Provenance

Source

Sunanda Sharma via figshare.

Collection Method

Data likely originates from a genetic suppressor screen in C. elegans, as described.

Freshness

Last updated 2026-04-15 18:01:07; freshness should be verified.