MpMetRS: Cryo-EM Structure of a Multi-Domain Methionyl-tRNA Synthetase Fusion

A structural analysis of the methionyl-tRNA synthetase gene product (MpMetRS) from Mycoplasma penetrans, resolved via cryo-EM. The dataset, authored by Behrouz Ghazi Esfahani and last updated on 2026-05-27, details a unique three-domain enzyme fusion. It is a small dataset of 5.5 KB, available in XLS format under a CC-BY-4.0 license.

Use Cases

• Modeling protein domain interactions based on the described N-terminal, AGAT, and MetRS domains
• Analyzing structural constraints for tRNA binding based on the described domain rotation
• Studying evolutionary mechanisms of gene fusion in condensed genomes like Mycoplasma penetrans

Strengths

• Structural resolution details are provided, with the N-terminal and AGAT domains resolved to 3.27 Å.
• The dataset is openly available under a permissive CC-BY-4.0 license.
• The description provides a specific biological context for the gene fusion in Mycoplasma penetrans.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (5.5 KB), indicating limited scope.

Provenance

Source

figshare, authored by Behrouz Ghazi Esfahani

Collection Method

Data likely derived from cryo-EM structural analysis as described.

Freshness

Last updated 2026-05-27 17:24:43; freshness should be verified.