nsSNPs and MIC Values for Six Antibiotics with Efflux Pump Inhibitor

29.7 KB dataset from figshare by Dominika Buni, last updated April 2026. It contains non-synonymous single nucleotide polymorphisms in potential efflux pump genes and the initial Minimum Inhibitory Concentration values for six antibiotics, measured both in the absence and presence of sodium orthovanadate.

Use Cases

• Correlate specific nsSNPs with changes in antibiotic MIC values based on the genetic and phenotypic data.
• Assess the impact of the efflux pump inhibitor sodium orthovanadate on antibiotic resistance levels.
• Identify candidate efflux pump genes through genetic variation and associated resistance phenotypes.

Strengths

• Data is openly licensed under CC-BY-4.0.
• File is in a standard, accessible XLSX format.
• Focuses on a specific, mechanistic aspect of antibiotic resistance.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection.

Provenance

Source

figshare, author Dominika Buni.

Collection Method

Likely contains experimental laboratory measurements of MIC values and genetic sequencing data.

Time Range

null

Freshness

Last updated 2026-04 17:40:25; freshness should be verified.

Geography

null