C. elegans Anthelmintic Drug Efficacy Scores Across Larval Stages

A dataset from figshare, last updated in April 2026, containing health-rating scores for the model organism C. elegans treated with various anthelmintic drugs. The data, created by Sam A. Attalla, compares drug efficacy against larval stage 1 (L1) and larval stage 4 (L4) worms to guide therapeutic development for soil-transmitted helminths.

Use Cases

• Compare drug potency across larval stages based on health-rating scores mentioned in the description
• Model dose-response relationships for anthelmintics based on concentration and mortality data
• Identify candidate drugs for environmental application strategies against hookworm larvae
• Benchmark new anthelmintic compounds against established drugs like albendazole and ivermectin

Strengths

• Data provides direct stage-to-stage comparisons for multiple anthelmintic drugs
• Includes tests with the mass drug administration drug albendazole and the potent drug ivermectin
• Dataset is openly available under a CC-BY-4.0 license

Limitations

• Dataset is very small at 5.5 KB, indicating limited scope
• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Experimental data from health-rating system scoring of individual C. elegans worms in varying drug concentrations.

Time Range

Experimental timeframe not specified; dataset metadata updated April 2026.

Freshness

Last updated 2026-04 17:55:13

Geography

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