Stella M. Schmelzle's dataset on figshare contains oligonucleotide sequences related to 3’-nucleotidases/nucleases in Leishmania major parasites. The 5.5 KB XLS file, last updated in 2026, supports research into purine salvage pathways and infection mechanisms. It was generated using quantitative proteomics and genome editing methods.
Use Cases
- Analyze enzyme activity patterns based on the described 3’-nucleotidase and endonuclease functions.
- Model host-pathogen interactions based on features related to extracellular adenosine generation and immune suppression.
- Identify potential drug targets based on the p1/s1 nuclease cluster described as pivotal for infection.
Strengths
- Data is associated with a specific, detailed research context on Leishmania major.
- The dataset is openly licensed under CC-BY-4.0 for reuse.
Limitations
- The dataset is very small at 5.5 KB, indicating limited scope.
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
Provenance
- Source
- figshare
- Collection Method
- Generated using quantitative proteomics, immunological assays, and genome editing methods.
- Freshness
- Last updated 2026-05-21 07:37:57