C. Elegans Ethanol Exposure and Sensorimotor Performance Data

Figshare hosts a dataset from a study on the effects of 24-hour ethanol exposure, withdrawal, and withdrawal relief on the nematode Caenorhabditis elegans. The research employed a kinetic chemotaxis assay, lifespan analysis, mobility tests, gene expression analysis, and imaging assays. Data includes results from wild-type, dopamine receptor mutant, and serotonin biosynthesis null mutant worms.

Use Cases

• Analyze sensorimotor performance differences in the kinetic chemotaxis assay between wild-type and mutant worms under ethanol exposure.
• Correlate gene expression analysis results with observed lifespan and mobility changes in C. elegans following ethanol treatment.
• Model drug tolerance using the 3-step experimental paradigm based on the kinetic chemotaxis behavioral assay.

Strengths

• Data is derived from multiple experimental assays including kinetic chemotaxis, lifespan, mobility, and gene expression analysis.
• Includes comparative results from three distinct genetic backgrounds: wild-type, a dopamine receptor mutant, and a serotonin biosynthesis null mutant.
• Dataset is openly available under a CC BY 4.0 license.

Limitations

• The dataset is very small at 5.5 KB, indicating limited scope and likely a summary of results rather than raw experimental data.
• Sample data and column structure are unavailable, limiting direct analysis of individual observations.
• Data is specific to the model organism C. elegans, which may limit direct translational insights for human alcohol use disorder.

Provenance

Source

Figshare, authored by Teresa Rubio-Tomás.

Collection Method

Experimental data from modified kinetic chemotaxis assays, lifespan tests, mobility assessments, gene expression analysis, and imaging on C. elegans.

Time Range

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Freshness

Last updated on 2026-03-23.

Geography

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