One-Way Sensitivity Analysis Results for PFO Closure Cost-Effectiveness in China

One-way sensitivity analysis results from a Markov cohort model evaluating the cost-effectiveness of patent foramen ovale closure for cryptogenic stroke in China. The dataset, shared by Chen Chen on figshare under CC-BY-4.0, was last updated in March 2026. It supports the study's conclusion that PFO closure is a dominant economic strategy, saving $4,045 per patient while adding 1.41 quality-adjusted life years.

Use Cases

• Validate the robustness of a health economic model based on one-way sensitivity analysis results.
• Analyze the influence of key parameters like time horizon and psychological comorbidity costs on incremental cost-effectiveness ratios.
• Compare cost-effectiveness outcomes for different stroke prevention strategies based on the provided Markov model states.
• Inform evidence-based resource allocation decisions for stroke prevention services using the Chinese willingness-to-pay threshold.

Strengths

• Results are derived from a defined Markov cohort model with four health states and a 30-year horizon.
• Analysis incorporates Chinese-specific cost data from multi-center hospital surveys and a defined willingness-to-pay threshold.
• Probabilistic sensitivity analysis showed a 94.2% probability of cost-effectiveness at the Chinese threshold.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 9.5 KB, indicating limited scope.

Provenance

Source

Chen Chen via figshare.

Collection Method

Derived from a Markov cohort model constructed for a health economic study.

Time Range

Model horizon is 30 years.

Freshness

Last updated 2026-03 17:23:35; freshness should be verified.

Geography

China (Chinese healthcare payer perspective).