Mouse Neurotoxicity Study Data from Open Field and Elevated Plus Maze Tests

Behavioral and immunohistochemistry data from a study examining the effects of maternal vitamin D on propofol-induced neurotoxicity in mouse offspring. The dataset includes results from open field and elevated plus maze tests conducted at postnatal day 45, alongside protein expression measurements from the hippocampus and prefrontal cortex at postnatal days 7 and 45. The data was published by Hüseyin Cihat Solmaz on figshare in May 2026 under a CC-BY-4.0 license.

Use Cases

• Analyze behavioral outcomes based on open field and elevated plus maze test results mentioned in the description
• Model relationships between vitamin D administration and protein expression levels of TNF-α, Bax, and Bcl-2
• Compare neuroinflammatory and apoptotic factor changes across different brain regions (hippocampus, prefrontal cortex) and time points (PN7, PN45)

Strengths

• Data is explicitly structured with four distinct experimental groups (C, P, D, PD) as described in the methodology
• Includes measurements from two specific brain regions and two postnatal time points, providing a multi-faceted view
• Published under a permissive CC-BY-4.0 license, facilitating reuse

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The dataset is very small at 9.7 KB, indicating limited scope

Provenance

Source

Hüseyin Cihat Solmaz via figshare

Collection Method

Experimental data from a controlled study on 20 pregnant mice and their offspring, involving immunohistochemistry and behavioral tests.

Time Range

Data collection likely corresponds to the experimental timeline described, culminating at postnatal day 45.

Freshness

Last updated 2026-05-22 18:00:33; freshness should be verified

Geography

Laboratory study; specific geographic location is not provided.