Biofilm Optical Density Measurements Before and After Compound Treatment

Optical density measurements quantify biofilm formation for three microbial species—S. aureus, E. coli, and C. albicans—before and after exposure to a test compound. The dataset, created by Saad Alghamdi, is a small experimental file of 5.5 KB in XLS format. It was last updated in April 2026.

Use Cases

• Compare pre-treatment and post-treatment OD values to assess the efficacy of compound 3i against each microbial species.
• Analyze OD differences between S. aureus, E. coli, and C. albicans biofilms to evaluate species-specific susceptibility.
• Use the before/after OD measurements as labeled data for training regression models to predict treatment outcomes.
• Benchmark the inhibitory effect of compound 3i by calculating percentage reduction in optical density for each biofilm sample.

Strengths

• Data includes measurements for three distinct, clinically relevant microbial species (S. aureus, E. coli, C. albicans).
• Explicit before-and-after treatment structure allows for direct calculation of compound effect.
• Published under a permissive CC-BY-4.0 license for clear reuse.

Limitations

• The dataset is very small at 5.5 KB, indicating a limited number of experimental replicates or samples.
• Unknown row count and specific column structure limit immediate assessment of statistical power.
• Lack of detailed metadata on experimental conditions (e.g., incubation time, compound concentration) may hinder replication.

Provenance

Source

Saad Alghamdi via figshare.

Collection Method

Laboratory measurement of biofilm optical density, likely using a microtiter plate reader.

Freshness

Last updated in April 2026.