Organ Weights and Lipid Profiles of SHRSP Rats on Cholesterol Diets

Dietary cholesterol reduced systolic blood pressure by 9–10% in stroke-prone hypertensive rats. This 5.5 KB Excel dataset contains organ weight and lipid profile data from a 12-week feeding study with three diet groups. Yutaro Nishikata published the data on figshare in 2026.

Use Cases

• Analyze the relationship between dietary cholesterol and organ weight changes based on the described experimental groups.
• Model the effect of cholesterol on systolic blood pressure based on the reported 9–10% reduction.
• Study alterations in lipid profiles, including phytosterol content and arachidonic acid ratios, as described in serum and kidney samples.
• Investigate correlations between renal histopathology findings and the described lipidomic changes.

Strengths

• Data is from a controlled 12-week feeding study with three distinct diet groups.
• Includes specific physiological outcomes like a 9–10% reduction in systolic blood pressure.
• Published under a permissive CC-BY-4.0 license for reuse.

Limitations

• Dataset is very small at 5.5 KB, indicating limited scope.
• Row count and column-level documentation are unknown, requiring manual inspection after download.
• Data is from a single rat strain (SHRSP/Izm) and sex (male), which may limit generalizability.

Provenance

Source

figshare, author Yutaro Nishikata

Collection Method

Experimental data from a controlled animal feeding study.

Freshness

Last updated 2026-05-21 17:27:02