UK Kidney Replacement Therapy Incidence and Outcomes by Primary Disease, 1999-2021

UK Renal Registry data for 10,308 primary glomerulonephritis and 8,302 ADPKD patients initiating kidney replacement therapy between 1999 and 2019, with follow-up to 2021. The dataset includes incidence rates, patient demographics, and survival outcomes by treatment modality. Stephen A Roberts published this analysis under a CC-BY-4.0 license in April 2026.

Use Cases

• Analyze temporal trends in KRT incidence based on primary disease and demographic factors mentioned in the description.
• Compare patient survival and graft outcomes based on treatment modality (transplantation, PD, haemodialysis) for different kidney diseases.
• Model the association between socioeconomic deprivation and KRT incidence rates using the multivariable regression framework described.
• Benchmark survival rates for primary glomerulonephritis subtypes against adult polycystic kidney disease as a reference.

Strengths

• Includes 10,308 primary glomerulonephritis and 8,302 ADPKD patient records from a national registry.
• Covers a long time series from 1999 to 2021, allowing analysis of trends.
• Provides specific incidence rates (e.g., 11.8 pmp for pGN) and survival statistics (e.g., 81.8% 10-year survival post-transplant for pGN).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is limited to patients with advanced disease requiring KRT, excluding those managed conservatively.

Provenance

Source

UK Renal Registry

Collection Method

Registry data analysis using multivariable Poisson regression and Cox regression models.

Time Range

1999-2021

Freshness

Last updated 2026-04-28 17:25:39; freshness should be verified.

Geography

United Kingdom