UK Kidney Replacement Therapy Incidence and Outcomes by Primary Disease, 1999-2021

1999-2021 data from the UK Renal Registry on adults initiating kidney replacement therapy (KRT). The dataset includes 10,308 patients with primary glomerulonephritis and 8,302 with adult polycystic kidney disease, with analysis of incidence rates, survival, and treatment modalities. It was authored by Stephen A Roberts and last updated in 2026.

Use Cases

• Analyzing temporal trends in KRT incidence based on primary disease and demographic factors mentioned in the description.
• Comparing patient survival and graft outcomes across different treatment modalities (transplantation, PD, haemodialysis).
• Modeling the association between socioeconomic deprivation and disease incidence using the multivariable regression framework described.
• Benchmarking outcomes for specific glomerulonephritis subtypes like IgAN and MN against a reference disease (ADPKD).

Strengths

• Includes 10,308 pGN and 8,302 ADPKD patient records from a national registry.
• Covers a long time range with patient follow-up from 1999 to December 2021.
• Analysis includes specific incidence rates (e.g., 11.8 pmp for pGN) and survival statistics (e.g., 81.8% 10-year post-transplant survival for pGN).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is limited to patients requiring KRT and does not capture those managed conservatively.

Provenance

Source

UK Renal Registry

Collection Method

Registry data analysis using multivariable Poisson and Cox regression models.

Time Range

1999-2021 (KRT initiation 1999-2019, follow-up to 2021)

Freshness

Last updated 2026-04-28 17:25:39; freshness should be verified.

Geography

United Kingdom