Pathway Enrichment of Up-Regulated Hippocampal Genes in Mice

Comprising pathway enrichment analysis results for up-regulated genes in the hippocampus of mice at 3 hours post status epilepticus (SE). It is a small dataset of 25.5 KB, provided in an XLSX file format. The data was contributed by Hui-Ling Tang and is licensed under CC BY 4.0.

Use Cases

• Identify significantly enriched biological pathways from the up-regulated gene list to understand molecular responses to SE.
• Analyze the relationship between specific up-regulated genes and their associated pathways for hypothesis generation in epilepsy research.
• Use the pathway enrichment results as a reference for cross-validation with other temporal or spatial gene expression datasets in neuroscience.

Strengths

• Dataset is openly licensed under CC BY 4.0, facilitating reuse and sharing.
• Focuses on a specific, time-point-defined biological context (hippocampus at 3h post-SE).
• Data is provided in the structured and widely accessible XLSX file format.

Limitations

• The dataset is very small at 25.5 KB, indicating limited scope and likely a small number of analyzed genes or pathways.
• No column names, sample data, or row count are provided, limiting understanding of the data structure and analytical depth.
• The specific methodology for gene selection and pathway analysis is not described, which affects reproducibility.

Provenance

Source

figshare, contributed by author Hui-Ling Tang.

Collection Method

Pathway enrichment analysis performed on up-regulated genes from a gene expression study.

Time Range

Biological data corresponds to a single time point: 3 hours post status epilepticus (SE).

Freshness

Last updated on March 20, 2026.