Plasma Gelsolin and Inflammatory Marker Levels in Pregnancy

Yumiko Miyazaki's pilot study dataset contains measurements of plasma gelsolin (pGSN), C-reactive protein (CRP), and white blood cell (WBC) counts from healthy pregnant women and patients with preterm premature rupture of membranes (PPROM). Data includes serial measurements from membrane rupture to delivery and samples from first, second, and third trimesters. The dataset was last updated on April 7, 2026.

Use Cases

• Analyze correlation between plasma gelsolin (pGSN) levels and C-reactive protein (CRP) in PPROM patients.
• Model the trend of white blood cell (WBC) count changes following membrane rupture until delivery.
• Compare plasma gelsolin concentration across first, second, and third trimester samples from healthy pregnancies.
• Investigate the relationship between immunohistochemical staining results for gelsolin in placental tissue and plasma biomarker levels.

Strengths

• Data includes serial measurements from membrane rupture to delivery for PPROM cases.
• Contains measurements for three specific biomarkers: pGSN, CRP, and WBC count.
• Dataset is openly licensed under CC-BY-4.0.

Limitations

• Dataset is very small at 9.5 KB, indicating a limited sample size typical of a pilot study.
• Specific row count and demographic details are unknown, limiting reproducibility assessments.
• Geographic origin and organizational provenance of the data are not specified.

Provenance

Source

Yumiko Miyazaki via figshare.

Collection Method

Plasma gelsolin measured by enzyme-linked immunosorbent assay (ELISA); inflammatory markers (CRP, WBC) via clinical tests; immunohistochemical staining performed on placental tissues.

Time Range

Covers pregnancy trimesters and period from membrane rupture to delivery.

Freshness

Last updated in April 2026.

Geography

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