Personal Amphibian Alkaloid Database for MZmine, 76 Adducts

Mabel Gonzalez's dataset contains 76 adducts from skin metabolite analyses of the poison frog Colostethus imbricolus. The data, last updated in April 2026, includes 33 adducts tentatively annotated as amphibian alkaloids and 25 matching natural products from the DNP. It was generated using TTX-targeted and untargeted profiling methods to investigate paralytic compounds.

Use Cases

• Comparative analysis of amphibian alkaloid profiles based on the 33 tentatively annotated compounds.
• Investigating sex-based variation in skin metabolomes based on the inter-individual analysis of six specimens.
• Method development for toxin separation based on the described normal-phase gradient approach for TTX.
• Identifying unknown natural products based on the 10 non-annotated molecular formulas.

Strengths

• Includes 76 common adducts from dual analytical methods.
• 33 adducts are tentatively annotated as specific amphibian alkaloids.
• Data is openly licensed under CC-BY-4.0.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• 10 molecular formulas remain non-annotated and lack MS/MS spectra for structural confirmation.

Provenance

Source

Mabel Gonzalez via figshare.

Collection Method

Generated via TTX-targeted separation and untargeted profiling of skin extracts from Colostethus imbricolus specimens.

Time Range

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Freshness

Last updated 2026-04-16 17:49:09; freshness should be verified.

Geography

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