Pharmacokinetic Parameters of T in Pregnant and Non-Pregnant Rats

Pharmacokinetic parameters of a substance (T) measured in rats after a single intraperitoneal injection of a 10 mg/kg dose. The dataset compares non-pregnant rats with rats on their 22nd day of pregnancy, with 5 animals per group. Data were analyzed using an unpaired t-test and are expressed as mean and standard deviation, authored by Saif-alnasr H. Mohammed and last updated on 2026-05-05.

Use Cases

• Compare drug exposure parameters between pregnant and non-pregnant states based on the described group comparison.
• Model pharmacokinetic profiles in pregnancy based on the reported mean and standard deviation values.
• Validate statistical methods for small-sample preclinical studies based on the use of an unpaired t-test.
• Benchmark results from similar intraperitoneal injection studies in rodent models.

Strengths

• Data includes a controlled comparison between two physiological states (non-pregnant vs. 22nd-day pregnant).
• Statistical analysis (unpaired t-test) and data expression (mean and SD) are explicitly stated.
• Dataset is openly licensed under CC-BY-4.0.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 5.5 KB, indicating limited scope.

Provenance

Source

figshare, author Saif-alnasr H. Mohammed.

Collection Method

Likely derived from a controlled laboratory experiment in rats.

Freshness

Last updated 2026-05-05 17:39:16; freshness should be verified.