A dataset from figshare by Nebat Ali, last updated March 2026. It contains plasmid data used for transformations of the thermally dimorphic fungal pathogen Histoplasma. The 2.0 KB CSV file supports research into the role of the histone deacetylase Rpd3 in regulating virulence and morphology in response to temperature.
Use Cases
- Identify plasmids used for genetic manipulation of Histoplasma based on the described experimental work.
- Study the relationship between histone deacetylase inhibition and yeast morphology at 37°C, as referenced in the description.
- Analyze regulatory components for activating pathogenesis and repressing filamentation programs in thermal dimorphism.
- Investigate chromatin regulation's role in temperature response and virulence factor expression in a fungal pathogen.
Strengths
- File size is precisely 2.0 KB, indicating a focused dataset.
- License is clearly defined as CC-BY-4.0, permitting reuse with attribution.
- Last update date is explicitly provided: 2026-03-17.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- Description metadata is limited; actual data quality requires manual inspection after download.
Provenance
- Source
- figshare
- Collection Method
- Likely contains plasmids used in laboratory experiments described in the associated research.
- Time Range
- null
- Freshness
- Last updated 2026-03 17:33:24; freshness should be verified.
- Geography
- null