PolyPhen-2 predictions for non-synonymous single nucleotide polymorphisms (nsSNPs) in the MBP gene. The table likely contains classifications of variants as benign, possibly damaging, or probably damaging based on PolyPhen-2 scores. The dataset was authored by Arwa Ibrahim Alwabran and published on figshare in May 2026.
Use Cases
- Assessing the potential pathogenicity of MBP gene variants based on PolyPhen-2 scores mentioned in the description
- Filtering candidate variants for further experimental validation based on predicted damage classifications
- Benchmarking variant prediction tools against PolyPhen-2 results for MBP
- Correlating predicted variant damage with known clinical phenotypes of MBP mutations
Strengths
- Dataset is openly licensed under CC-BY-4.0
- File size is 16.4 KB, indicating a focused and manageable scope
Limitations
- Row count is unknown, which may limit suitability assessment
- Column-level documentation is absent; field semantics must be inferred after download
Provenance
- Source
- figshare
- Freshness
- Last updated 2026-05-21 17:28:27; freshness should be verified