Primer and siRNA Sequences for CMA Research in Gastric Cancer

Primer and small interfering RNA sequences used in a study of chaperone-mediated autophagy in gastric cancer cells. The dataset is 5.5 KB in size, shared by Shuangshuang Le on figshare under a CC-BY-4.0 license, and was last updated on May 15, 2026. The research focused on the LAMP2A–DJ-1 regulatory axis and its role in oxidative stress resistance.

Use Cases

• Replicate genetic knockdown experiments based on the siRNA sequences described.
• Design follow-up qPCR assays based on the provided primer sequences.
• Study sequence motifs for CMA substrate recognition, such as the KFERQ-like motif mentioned.
• Analyze gene expression data related to LAMP2A, DJ-1, BAX, and Bcl-2 from the described experimental models.

Strengths

• Dataset is openly shared under a permissive CC-BY-4.0 license.
• Specific research context involving gastric cancer and oxidative stress is clearly described in the accompanying publication.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 5.5 KB, indicating limited scope.

Provenance

Source

Shuangshuang Le

Collection Method

Generated as part of a research study on chaperone-mediated autophagy in gastric cancer.

Freshness

Last updated 2026-05-15 17:36:42; freshness should be verified.