Primers: Single-Cell RNA-Seq Data on Host Response to Sendai Virus Infection

Primers is a 10.3 KB dataset by Yanling Yang, last updated in April 2026. It contains single-cell RNA-sequencing data analyzing the host response to Sendai virus infection, with a focus on copy-back viral genomes. The dataset is shared under a CC-BY-4.0 license on figshare.

Use Cases

• Modeling temporal shifts in host transcriptional states based on the described progression from antiviral to inflammatory programs.
• Identifying gene expression signatures associated with copy-back viral genome (cbvg) status in infected cells.
• Analyzing cell-to-cell communication of interferon and chemokine programs between cbvg-positive and cbvg-negative cell populations.

Strengths

• Data is derived from a described single-cell RNA-sequencing and computational framework, providing high-resolution cellular insights.
• Dataset is openly licensed under CC-BY-4.0, permitting reuse and redistribution.
• Explicitly maps a temporal cellular response, capturing early and late infection stages.

Limitations

• Row count is unknown, which may limit suitability assessment for large-scale analyses.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 10.3 KB, indicating limited scope or a highly focused subset of data.

Provenance

Source

Yanling Yang

Collection Method

Generated via a described single-cell RNA-sequencing and computational framework during Sendai virus infection experiments.

Time Range

Temporal coverage spans the described course of infection from early to late stages.

Freshness

Last updated 2026-04-27 17:43:59; freshness should be verified.

Geography

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