Primers for qRT-PCR in Progesterone Receptor and GRHL2 Gene Regulation Study

Primers used for quantitative reverse transcription polymerase chain reaction (qRT-PCR) in a study of progesterone receptor (PR) and grainyhead-like 2 (GRHL2) interactions. The 5.5 KB XLS file, authored by Marleen T. Aarts and last updated in March 2026, is shared under a CC-BY-4.0 license on figshare. It supports research into how these transcription factors coordinate gene regulation through chromatin binding and 3D genome architecture in hormone-responsive breast cancer cells.

Use Cases

• Designing qRT-PCR experiments based on the provided primer sequences.
• Analyzing co-regulation of target genes based on the described interaction between PR and GRHL2.
• Investigating chromatin looping and 3D genome architecture modifications mentioned in the study context.
• Validating gene expression findings related to progesterone receptor activity in breast cancer models.

Strengths

• File size is 5.5 KB, indicating a focused and likely easily manageable dataset.
• Dataset is associated with a specific, peer-reviewed research study on transcriptional co-regulation.
• License is CC-BY-4.0, permitting broad reuse with attribution.

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment.
• Description metadata is limited; actual data quality and structure require manual inspection after download.

Provenance

Source

figshare

Collection Method

Likely generated as part of a laboratory study on transcription factor interactions.

Time Range

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Freshness

Last updated 2026-03-17 17:33:08; freshness should be verified.

Geography

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