Western Blot Protein Expression in Intracerebral Hemorrhage Mouse Model

Figshare hosts a small dataset of protein expression levels measured by Western blot. It contains quantitative results from a study investigating the effects of GABAAR modulators CL218872 and MRK-016 on synaptic plasticity in a mouse model of intracerebral hemorrhage. The data is provided in a single XLSX file sized 12.4 KB.

Use Cases

• Analyze protein expression levels for synaptic markers like BDNF, GAP-43, PSD-95, and synaptophysin across treatment groups.
• Compare Western blot results for inflammatory markers phospho-p65, IL-6, and TNF-α between mice treated with CL218872 and MRK-016.
• Correlate protein expression data with histological and neurobehavioral outcomes described in the associated study.

Strengths

• Data is directly linked to a detailed, peer-reviewed experimental study on intracerebral hemorrhage.
• The dataset is shared under the permissive CC BY 4.0 license, allowing for broad reuse.
• File is provided in the widely compatible XLSX format for tabular data.

Limitations

• The dataset is very small at 12.4 KB, indicating limited scope and likely a low number of observations or samples.
• No column names, row counts, or sample data are provided, making the data structure and volume unclear.
• Data is specific to a single animal model study, limiting direct generalizability to human conditions.

Provenance

Source

Tingting Chen via figshare

Collection Method

Experimental data from Western blot analysis of mouse brain tissue following induced intracerebral hemorrhage and drug treatment.

Time Range

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Freshness

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Geography

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