Proteomics Data for E. Histolytica Trophozoites from Mass Spectrometry

Eva Zanditenas's dataset contains proteomics data showing proteins up- and down-regulated in Entamoeba histolytica trophozoites, detected by mass spectrometry. The data was analyzed using DIA-NN 1.9.1 and Perseus 1.6.7.0 against the E. histolytica proteome from UniProt with a 1% FDR threshold. It was last updated on April 13, 2026.

Use Cases

• Identify significantly changed proteins based on T-test and log2 fold change values.
• Analyze protein quantitation and intensity levels across different sample conditions (WT, WT+I, ADI).
• Filter protein identifications based on peptide count thresholds mentioned in the description.
• Perform statistical validation of proteomics data using the described FDR threshold and analysis pipeline.

Strengths

• Data processed with a 1% false discovery rate (FDR) threshold for identification and quantification.
• Analysis performed using specific, named software tools: DIA-NN 1.9.1 and Perseus 1.6.7.0.
• Dataset is 2.3 MB in size, indicating a focused and manageable download.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Proteins were cleaved with trypsin and analyzed by LC/MSMS using an Exploris480 mass spectrometer in DIA mode.

Time Range

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Freshness

Last updated 2026-04-13 17:41:18; freshness should be verified.

Geography

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