Proteomics data from a study investigating how poxviruses, including vaccinia virus (VACV) and Modified Vaccinia Virus Ankara (MVA), manipulate host cell autophagy pathways to facilitate viral replication. The dataset, authored by Kang Niu and last updated in April 2026, is shared under a CC-BY-4.0 license on figshare. It is a 27.1 KB XLSX file, suggesting a small-scale, focused experimental dataset.
Use Cases
- Analyze viral protein-host protein interactions based on the described role of VACV protein A52.
- Model autophagy pathway disruption based on the described blockade of autophagosome-lysosome fusion.
- Investigate host restriction factors based on the identified role of SNAP29 in limiting MVA replication.
- Compare viral strain effects based on the differential autophagy modulation by VACV versus MVA.
Strengths
- Data is shared under a permissive CC-BY-4.0 license, enabling reuse and redistribution.
- The dataset is focused on a specific, well-described biological mechanism involving VACV, MVA, and autophagy.
- File format is XLSX, which is widely accessible for analysis.
Limitations
- Row count and column-level documentation are absent; field semantics must be inferred after download.
- The dataset is very small (27.1 KB), indicating limited scope and likely a focused experimental result set.
- Description metadata is limited; actual data quality and completeness require manual inspection after download.
Provenance
- Source
- figshare, author Kang Niu.
- Collection Method
- Likely contains experimental proteomics data from the described virology study.
- Time Range
- null
- Freshness
- Last updated 2026-04-13 17:35:38; freshness should be verified.
- Geography
- null