Rabbit Model Data on Maternal Undernutrition and Offspring Development

A rabbit model study investigates effects of maternal food restriction during gestation on F1 female offspring health and F2 oocyte gene expression. The dataset includes measurements of body composition, metabolic profiles, growth trajectories, and molecular markers like SOD2, G6PD, and FABP4 mRNA levels. Data was collected by María Arias-Alvarez and published on figshare in 2026.

Use Cases

• Analyze correlations between maternal diet group (Control vs. FR) and offspring serum aminotransferase levels to assess hepatic stress.
• Model the relationship between progesterone/estradiol ratio at ovulation and the proportion of expanded blastocysts in F2 embryos.
• Compare gene expression levels of TP53 and CASP3 in cumulus cells (CCs) between dietary treatment groups.
• Examine growth trajectory data from birth to 16 weeks for F1 females against their maternal dietary background.

Strengths

• Includes molecular data on oocyte gene expression (SOD2, G6PD, FABP4) and cumulus cell transcripts (TP53, CASP3).
• Contains longitudinal health metrics for offspring, tracking body composition and metabolic profiles from birth to sexual maturity.
• Data is licensed under CC BY 4.0, permitting open sharing and adaptation.

Limitations

• Small data scale indicated by 41.4 KB file size, suggesting limited sample size or variable count.
• Dataset scope is restricted to a specific rabbit model study, limiting generalizability to other species.
• Temporal coverage and exact sample/row counts are not provided in the input.

Provenance

Source

figshare, authored by María Arias-Alvarez.

Collection Method

Experimental data from a controlled study on pregnant rabbits fed ad libitum (Control) or a restricted diet (FR group).

Time Range

Covers from gestation through offspring development to 16 weeks of age.

Freshness

Last updated in March 2026.

Geography

null