VEEV Antibody Efficacy Data in Cynomolgus Macaques

Venezuelan equine encephalitis virus (VEEV) research data from a study using cynomolgus macaques. The dataset contains raw data for figures from experiments testing prophylactic and therapeutic intravenous and intranasal antibody treatments against aerosol challenge with IA/B and IC clade viruses. The data was authored by Chengqun Sun and last updated on figshare in April 2026.

Use Cases

• Modeling the relationship between antibody treatment timing and reduction in febrile response based on the described experimental design.
• Comparing the efficacy of intravenous versus intranasal antibody delivery routes against different viral clades.
• Analyzing the impact of lyophilized versus liquid antibody preparations on viremia levels.
• Validating preclinical models for VEEV based on non-human primate challenge data.

Strengths

• Data is explicitly linked to a peer-reviewed publication (Gardner et al., J. Virol., 2017).
• Includes results from both prophylactic (24 hr before) and therapeutic (24 hr after) treatment timelines.
• Covers challenge with two distinct VEEV subtypes (IA/B and IC clade).
• Available under a permissive CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 1.0 MB file size suggests a relatively small dataset.

Provenance

Source

figshare

Collection Method

Experimental data from a non-human primate study.

Time Range

Study period not specified; dataset updated in 2026.

Freshness

Last updated 2026-04-27 17:24:33; freshness should be verified.

Geography

Laboratory study; geographic origin of data not specified.