SFTSV Mouse Model Data on Complement Hyperactivation and Spleen Injury

Raw data from a study investigating complement hyperactivation in Severe Fever with Thrombocytopenia Syndrome virus infection. The dataset, 1003.6 KB in size, was published by author Yan Liu on figshare under a CC-BY-4.0 license and last updated on April 15, 2026. It contains experimental results from a lethal mouse model using IFNAR−/− mice.

Use Cases

• Analyze the relationship between SFTSV infection and complement component C3 production based on the described mouse model data.
• Model the effects of C3aR antagonist treatment on viral load and survival time based on the experimental intervention described.
• Investigate transcriptional regulation of C3 and Cfb genes in fibroblastic reticular cells based on the described molecular pathways.
• Correlate spleen injury markers with inflammatory response data from the described infection model.

Strengths

• Data is associated with a specific, peer-reviewed research question on complement hyperactivation in SFTSV.
• Dataset is openly licensed under CC-BY-4.0, permitting reuse and redistribution.
• File size of 1003.6 KB suggests a focused, manageable dataset for analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is derived from a specific IFNAR−/− mouse model, which may limit generalizability.

Provenance

Source

figshare

Collection Method

Experimental data generated from a lethal mouse model of SFTSV infection.

Freshness

Last updated 2026-04-15 18:20:12; freshness should be verified.