KSHV K8 and ATF3 Interaction Data for Lytic Replication Study

Jiazhen Dong published raw data on Kaposi’s Sarcoma-associated herpesvirus (KSHV) lytic replication on figshare in May 2026. The data likely contains experimental results on the interaction between viral protein K8 and host transcription factor ATF3. The dataset is stored in an XLSX file sized 60.6 KB.

Use Cases

• Analyzing protein-protein interactions based on the described K8-ATF3 binding.
• Studying transcriptional regulation based on the repression of K8 promoter activity by ATF3.
• Investigating antiviral mechanisms based on ATF3's role in impairing KSHV lytic replication.
• Modeling host-pathogen dynamics based on the antagonistic role of viral LANA on ATF3 expression.

Strengths

• Data is published under a permissive CC-BY-4.0 license.
• The dataset is focused on a specific molecular mechanism in KSHV replication.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Jiazhen Dong

Collection Method

Likely contains experimental results from molecular biology assays described in the abstract.

Freshness

Last updated 2026-05-11 17:41:08; freshness should be verified.