Traumatic Brain Injury Biomarker Levels and Clinical Scores

A figshare dataset by Saiqa Nazeer contains clinical biomarker data for traumatic brain injury (TBI). It includes serum interleukin (IL)-1β and IL-18 levels and Glasgow Coma Scale scores for 40 TBI patients and 40 healthy control subjects. The dataset was last updated in April 2026.

Use Cases

• Correlate Glasgow Coma Scale scores with serum IL-1β and IL-18 levels to assess biomarker association with TBI severity.
• Compare IL-1β and IL-18 concentration distributions between the 40 TBI patients and the 40 healthy control subjects.
• Calculate diagnostic performance metrics like AUC, sensitivity, and specificity using the provided biomarker cut-off points.
• Investigate the correlation between IL-1β and IL-18 levels within the TBI patient cohort.

Strengths

• Includes a matched control group of 40 healthy subjects.
• Reports specific statistical results like AUC values and p-values for biomarker differences.
• Data is structured in an XLSX file for direct analysis.

Limitations

• Small sample size of only 80 total subjects (40 patients, 40 controls).
• Limited to mild-to-moderate TBI cases with a mean GCS score of 11.05.
• Dataset size is only 12.6 KB, indicating limited scope and few variables.

Provenance

Source

Saiqa Nazeer via figshare.

Collection Method

Data collected via a clinical study using enzyme-linked immunosorbent assay (ELISA) kits on human serum samples.

Freshness

Last updated in 2026.