C. Elegans Ethanol Exposure Sensorimotor and Lifespan Data

Teresa Rubio-Tomás's 2026 figshare dataset contains raw experimental data on the effects of 24-hour ethanol exposure, withdrawal, and withdrawal relief on Caenorhabditis elegans. The study includes results from a modified kinetic chemotaxis assay, lifespan and mobility assays, gene expression analysis, and imaging. It compares wild-type, dopamine receptor mutant, and serotonin biosynthesis null mutant worm responses.

Use Cases

• Analyze locomotion differences from the kinetic chemotaxis assay across wild-type, dopamine receptor mutant, and serotonin biosynthesis null mutant worms.
• Correlate 24-hour ethanol exposure levels with lifespan and mobility assay results for different genetic strains.
• Investigate gene expression data for stress response genes altered by ethanol exposure and withdrawal phases.
• Model drug tolerance using the 3-step experimental paradigm based on the diacetyl race behavioral data.

Strengths

• Data originates from a structured experimental model with three defined phases: exposure, withdrawal, and withdrawal relief.
• Includes comparative analysis across three distinct genetic worm strains: wild-type, dopamine receptor mutant, and serotonin biosynthesis null mutant.
• Assesses multiple biological endpoints: sensorimotor performance, lifespan, mobility, gene expression, and neuronal imaging.

Limitations

• The dataset is very small at 44.4 KB, indicating limited sample size and scope for robust statistical modeling.
• Specific row counts, column structures, and sample data are unavailable, hindering immediate assessment of data shape and completeness.
• Data is specific to the Caenorhabditis elegans model organism, limiting direct applicability to human systems without translational research.

Provenance

Source

Teresa Rubio-Tomás via figshare.

Collection Method

Experimental data from modified kinetic chemotaxis ('diacetyl race'), lifespan, mobility, gene expression, and imaging assays on C. elegans.

Time Range

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Freshness

Last updated March 23, 2026.

Geography

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