Raw Aorta Fluorescence Images from Mouse Atherosclerosis Study

55.0 MB of raw fluorescence microscopy images showing ROS staining in mouse aortas from a study on the anti-atherosclerotic effects of a polyphenol extract. The dataset, authored by He-Ping Liu and shared under CC-BY-4.0, was last updated in May 2026. Images were generated to investigate lipid plaques, oxidative stress, and CD36 protein expression in ApoE-deficient mice fed a high-fat diet.

Use Cases

• Training image segmentation models to quantify aortic lipid plaques based on Oil Red O and fluorescence staining.
• Analyzing patterns of reactive oxygen species (ROS) distribution in atherosclerotic lesions.
• Correlating fluorescence intensity from CD36 immunofluorescence with disease progression stages in mouse models.
• Benchmarking computer vision algorithms for feature extraction from complex histological image sets.

Strengths

• Dataset size is precisely quantified as 55.0 MB.
• License is clearly defined as CC-BY-4.0, permitting broad reuse with attribution.
• The experimental context is described in detail, including the use of ApoE-/- mice and a 12-week high-fat diet induction.

Limitations

• Row count and specific image dimensions are unknown, which may limit suitability assessment for certain tasks.
• Column-level documentation is absent; image metadata and file naming conventions must be inferred after download.
• Description metadata is limited; actual data quality and annotation completeness require manual inspection.

Provenance

Source

figshare, author He-Ping Liu

Collection Method

Generated via fluorescence staining (ROS, immunofluorescence) and histological staining (Oil Red O, H&E) of aorta tissue from a controlled mouse study.

Freshness

Last updated 2026-05-05 17:35:36

Geography

Study likely conducted in a research institution in China, given the focus on an ethnic herb from Yunnan province.