Oil Red O Stained Aorta Images from Atherosclerosis Mouse Study

61.1 MB of raw histological images showing Oil Red O staining of aorta bulk from a study on atherosclerosis in ApoE-/- mice. The dataset was created by He-Ping Liu and last updated on 2026-05-05. It supports research into the effects of a polyphenol extract on suppressing lipid plaques and hepatic lipid accumulation.

Use Cases

• Training image segmentation models to quantify lipid plaque area in aortic tissue based on staining patterns described in the study.
• Analyzing morphological changes in aorta and liver tissue due to high-fat diet and treatment interventions mentioned in the description.
• Developing computer vision pipelines for histological image analysis to assess the anti-atherosclerotic effects of herbal extracts.
• Correlating visual staining intensity with biochemical markers like serum lipid profiles and inflammatory cytokines referenced in the research.

Strengths

• Dataset size is 61.1 MB, indicating a specific collection of image files.
• Images are associated with a detailed experimental protocol using ApoE-/- mice on a high-fat diet for 12 weeks.
• Data is shared under a permissive CC-BY-4.0 license, allowing for reuse and modification.

Limitations

• Row count and specific image dimensions are unknown, which may limit suitability assessment.
• Column-level documentation is absent; image metadata and file organization must be inferred after download.
• The dataset appears focused on a single, specific experimental model, which may limit generalizability.

Provenance

Source

figshare

Collection Method

Images were generated from histological staining (Oil Red O and H&E) of aorta and liver tissues from a controlled mouse study.

Freshness

Last updated 2026-05-05 17:35:22; freshness should be verified.