Raw Images of Oil Red O Staining of Aortic Root from a Mouse Atherosclerosis Study

ApoE-/- mice on a high-fat diet were used to study atherosclerosis over 12 weeks. The dataset contains raw images of Oil Red O and H&E staining for aortic root, aorta bulk, and liver morphology, shared under a CC-BY-4.0 license by He-Ping Liu. The data was last updated on May 5, 2026.

Use Cases

• Quantifying lipid plaque area in aortic roots based on Oil Red O staining images.
• Training computer vision models to segment stained tissue regions in histological images.
• Correlating morphological changes in liver and aorta with treatment effects described in the study.
• Validating image analysis pipelines for cardiovascular disease research using a controlled mouse model.

Strengths

• Dataset size is 20.4 MB, indicating a focused collection of raw image files.
• Data is associated with a specific, described in vivo experiment using ApoE-/- mice over a 12-week period.
• Images are from multiple staining techniques (Oil Red O and H&E) allowing for multi-modal morphological analysis.

Limitations

• Row and column counts are unknown, making the scale and structure of the data difficult to assess prior to download.
• Description metadata is limited; actual data quality, resolution, and annotation details require manual inspection after download.
• The dataset appears to be a single snapshot from one study; its generalizability to other models or conditions is unknown.

Provenance

Source

figshare, author He-Ping Liu

Collection Method

Images generated from histological staining (Oil Red O, H&E) of tissues from a controlled mouse model study.

Time Range

Study involved a 12-week high-fat diet induction period; specific data collection dates are not provided.

Freshness

Last updated 2026-05-05 17:35:19; freshness should be verified.

Geography

The research is associated with an ethnic herb from Yunnan province, China, but the experimental location is not specified.