AD169-ΔUS2-Infected Cells: RNA-seq and GO Analysis of 1630 Differentially Expressed Genes

1630 differentially expressed genes identified via RNA-seq in AD169-ΔUS2-infected cells with or without LMAN2L expression. The dataset includes raw RNA-seq data and Gene Ontology functional enrichment analysis results, shared by Yue-Peng Zhou on figshare. It was last updated on 2026-05-18.

Use Cases

• Identify host cell transcriptional changes based on RNA-seq data from HCMV-infected cells.
• Perform functional enrichment analysis based on the provided Gene Ontology (GO) results.
• Investigate the role of the host factor LMAN2L in viral infection based on differential expression profiles.
• Validate or compare findings related to the AD169 HCMV strain and its US2 gene deletion mutant.

Strengths

• Focuses on 1630 differentially expressed genes, providing a specific target for analysis.
• Includes both raw RNA-seq datasets and processed GO enrichment analysis.
• Available under a permissive CC-BY-4.0 license for reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is relatively small at 3.9 MB, which may indicate limited scope or pre-filtered data.

Provenance

Source

figshare

Collection Method

RNA sequencing and bioinformatic analysis of infected cell cultures.

Freshness

Last updated 2026-05-18 17:39:42; freshness should be verified.