HIV-1 Viral Titer Assay Raw Imaging Data

11.9 MB of raw values from a high-content imaging reporter assay using modified GHOST cells to measure HIV-1 infection. The dataset, created by Teresa LuPone, facilitates direct correlation between infectivity and p24 secretion for studying viral replication kinetics.

Use Cases

• Correlate fluorescence intensity from imaging with p24 secretion data to model HIV-1 infection kinetics.
• Analyze raw imaging values to benchmark viral infectivity and tropism across different experimental samples.
• Use assay values to study the proportion of non-infectious virions in the context of antiretroviral therapy.

Strengths

• Data originates from a published high-content imaging assay designed for consistency and replicability.
• Assay enables rapid evaluation of large sample numbers and integrates with existing p24 analysis pipelines.

Limitations

• Specific row count and column structure are unknown, limiting assessment of dataset scale and feature diversity.
• Data is confined to a specific experimental system (GHOST cells), which may not generalize to other cell types or in vivo conditions.

Provenance

Source

figshare, authored by Teresa LuPone.

Collection Method

High-content imaging reporter assay using modified human osteosarcoma (GHOST) cells expressing HIV-1 receptors.

Time Range

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Freshness

Last updated March 2026.

Geography

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