Kat6a Knockout RNA-Seq: Differentially Expressed Genes and GO Terms in NSPCs

Anne K. Voss published RNA sequencing results comparing proliferating neural stem/progenitor cells (NSPCs) with and without the Kat6a gene. The dataset, last updated in May 2026, contains two tabs: one listing differentially expressed genes and another with Gene Ontology term annotations for those genes. The file is a 2.5 MB XLSX spreadsheet shared under a CC-BY-4.0 license.

Use Cases

• Identify gene expression changes in Kat6a-deficient neural stem cells based on the differential expression analysis.
• Perform functional enrichment analysis based on the provided Gene Ontology term annotations.
• Validate or compare findings on the role of Kat6a in neural stem cell proliferation.
• Integrate differential expression results with other omics datasets for systems biology studies.

Strengths

• Data is structured into two distinct, logically organized tabs for genes and functional annotations.
• Dataset is shared under a permissive CC-BY-4.0 license, facilitating reuse.
• File size of 2.5 MB indicates a manageable, focused dataset for analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for some statistical methods.
• Description metadata is limited; actual data quality and normalization methods require manual inspection.

Provenance

Source

figshare, author Anne K. Voss

Collection Method

RNA sequencing of proliferating Kat6a knockout versus wild-type NSPCs.

Time Range

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Freshness

Last updated 2026-05-04 17:43:49; freshness should be verified.

Geography

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