Single-Cell TCR and BCR Sequencing Data for Pathogen Study

802.7 KB of single-cell T-cell receptor (scTCRseq) and B-cell receptor (scBCRseq) sequencing data supporting specific figures in a published research article. The dataset was authored by Taeyong Kwon and uploaded to Figshare in April 2026. It provides the underlying cellular receptor data used to generate Figures 7 and 8 of the associated study.

Use Cases

• Analyze clonal expansion by quantifying unique T-cell receptor (TCR) sequences and their frequencies.
• Investigate B-cell receptor (BCR) isotype usage and somatic hypermutation patterns from the sequencing data.
• Correlate specific TCR or BCR clonotypes with cell metadata likely present in the XLSX file, such as sample or cluster identifiers.
• Validate immune repertoire findings from the associated publication's Figures 7 and 8 using the raw data.

Strengths

• Data is directly linked to a peer-reviewed publication in PLOS Pathogens, providing context and validation.
• Available under a permissive CC-BY-4.0 license for reuse and redistribution.

Limitations

• The dataset is small at 802.7 KB, indicating a limited scope, likely from a specific experiment or cohort.
• Unknown row count and column structure limit immediate assessment of data volume and features.
• Lacks explicit sample identifiers, clinical metadata, or detailed processing steps within the provided description.

Provenance

Source

Figshare, associated with a PLOS Pathogens article (doi:10.1371/journal.ppat.1014094).

Collection Method

Single-cell RNA sequencing (scRNA-seq) with enrichment for T-cell and B-cell receptor transcripts.

Freshness

Last updated on the platform in April 2026.